Plant Extracts

HPNSFEED (Eucommia Ulmoides P.E.) —— Natural Plant Extract

Eucommia ulmoides leaves is one kind of natural Chinese herbal medicine feed additives, chlorogenic acid as its main constituents has the functions of bacteriostat, anti-stress, antioxidant, eliminate free radicals, promote growth and improve the meat quality. 

Active Ingredient:

Chlorogenic acid: 5%min.    Polysaccharide: 20% min.     Flavonoid: 8%min.

Mechanism:

1. Broad-spectrum bacteriostasis

There is a significant inbibitional effect for a variety of bacteria by combined action of Chlorogenic acid, flavonoids and other compound. Vitro antibacterial test results show that minimum inhibitory concentration (mic) of staphylococcus aureus, beta streptococcus is 0.0625g/ml; For minimal inhibitory concentrations (mic) of escherichia coli, salmonella typhi were 0.5g/ml and 0.25g/ml, mechanism for noncompetitive inhibition of bacteria arylamine acetyltransferase, so that the arylamine in the bacterium body is accumulated, the metabolism of bacteria is disorder, then the bacteria can't normal growth and reproduction.

2. Antioxidation, eliminate the free radical

Chlorogenic acid is an effective phenolic antioxidant, its antioxidant capacity is better than coffeic acid, para hydroxy benzoic acid, ferulic acid, syringic acid, butyl hydroxy anisol (BHA) and tocopherol. Mechanism is that Catechol Hydroxyl structure in Chlorogenic acid which can increase the electron cloud density on the hydroxyl group, and also can form intramolecular hydrogen bond to reduce bond energy of O-H, Phenolic hydroxyl group on the hydrogen reaction is easy to occur which means to have strong antioxidant capacity.

3. Protecting liver and gallbladder

From the animal experiment, Chlorogenic acid has obvious protection functions on the liver injury that caused by Carbon tetrachloride (CCl4), acetaminophen and Cadmium, lower the severity of the liver pathological damage obviously which reduced the number of necrosis or rate of necrosis occurred.

 Mechanism: firstly, by inhibiting cytochrome P-450 drug enzyme metabolic system, induce of glucuronic acid of liver combine desmoenzyme activity, strengthen the combined metabolism of acetaminophen glucuronic acid which can enhance the detoxification metabolism of the acetaminophen in the body, reduce acetaminophen toxic metabolites; secondly, induce liver to combine plenty of metal thiol protein(MT) , the MT can combine Cadmium, which can reduce Cadmium distribution of macromolecular protein in nucleus, mitochondria, microsome and cytoplasm, thus reducing cadmium toxicity of liver cell; Thirdly, can promote bile secretion, accelerate the excretion of toxins.

4. Stimulate the gastrointestinal digestion system

Significantly increase on pharmacological effects in gastrointestinal peristalsis and promoting the gastric secretion, which can improve the animal digestion and nutrients absorption, improve the utilization rate of nutrients, then promote animal growth, improve the production performance.

Functions:

1. To prevent and treat disease, it can kill staphylococcus aureus, streptococcus, Coli, some parasites and virus, prevent and treat some acute gastrointestinal bacterial disease and coccidiosis.

2. To promote growth, improve productivity performance and feed conversion rate, FCR can be increased 7—10%.

3. To enhance the body resistance, improve the survival rate, reduce the diarrhea, and the diarrhea rate of piglet decreased the 8--10%.

4. To improve digestion, promote feed intake, stimulate the secretion of bile and pancreatic fluid, enhance the activity of digestive enzyme.

5. To improve muscle strength, decrease muscle fiber roughness and body fat content, to improve the flavor and water holding capacity of meat.

Dosage:

For Poultry

Species	Dosage（g/t）	Species	Dosage（g/t）
Broiler, meat duck（0-3 Weeks）	100--150	Chick	100--150
Broiler, meat duck（4-6 Weeks）	80--100	Young chicken	80--100
Broiler, meat duck （>6 Weeks）	80--100	Layer	80--100

For Swine

Species	Dosage（g/t）	Species	Dosage（g/t）
Piglet	150--250	Shoat	80--100
Big pig	80--100	Boar	80--100

For Aquatic animals

Species	Dosage（g/t）	Species	Dosage（g/t）
Fish	100—120	Eel	150--200
Shrimp, Crab	120--150

Remark: Eucommia Ulmoides P.E can be extra added, or used with antibiotics together, it can replace part of antibiotics of the feed, such as zinc bacitracin, flavomycin, etc.

Packing:  25 kg/barrel.

Shelf life:  24 months

Storage:  Stored in shaded dry, cool place with good ventilation.